DNA Repair Malignancies Annotation Platform is a repository where the information of different malignancies like Colorectal cancer (CRC) and Hereditary Non-polysis Colorectal Cancer (HNPCC) related to Mismatch Repair (MMR) and Microsatellite Instability (MSI). In the database, the interactions, location, protein and RNA expression, gene ontology and functions of the genes.
Future Aspect
More information will be incorporated related to MMR and MSI genes involved in CRC, HNPCC and database will be updated on a regular basis to help users get state-of-the-art information.
Objectives
The objective of the database is to study the part of the genes that are related to CRC and HNPCC. We wish to design it to help people to have an easy access and is usage. The main objectives of the database are:
a) Protein coding genes are being targeted to explore their regulatory function in CRC and HNPCC.
b) Study of gene interactions.
c) Study of Gene Ontology i.e., cellular components, molecular functions, biological processes that are related to the MMR and MSI involved in HNPCC and CRC.
d) Study of RNA and Protein Expression in colon tissues.
e) Study of sub-cellular and chromosomal locations.
f) Study of the functions of the genes related to involvement in MSI, MMR, HNPCC and CRC.
